BDBM50352272 CHEMBL1822447

SMILES CC(C)NC1(CNC(=O)N2CCC(CC2)c2nc(no2)-c2ccc3ccccc3n2)CCCC1

InChI Key InChIKey=AMHUWKSEZZAQOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50352272   

TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352272(CHEMBL1822447)
Affinity DataIC50:  58nMAssay Description:Displacement of BODIPY-cyclopamine from Smo expressed in COS-1 cells after 4 to 6 hrs by Flow Cytometry analysis in presence of 20% normal human seru...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSmoothened homolog(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50352272(CHEMBL1822447)
Affinity DataIC50:  16nMAssay Description:Displacement of BODIPY-cyclopamine from Smo expressed in COS-1 cells after 4 to 6 hrs by Flow Cytometry analysis in presence of 2% fetal calf serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed