BDBM50353788 CHEMBL1829433

SMILES CC(C)C(N(CCCN)C(=O)c1ccc(C)cc1)c1nc2snc(C)c2c(=O)n1Cc1ccccc1

InChI Key InChIKey=SMFXSYMLJDHGIE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50353788   

TargetKinesin-like protein KIF11(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF11(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant C-terminal His6-tagged KSP ATPase activity after 1 hr by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-like protein KIF23(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant GST-MKLP1 after 20 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKinesin-1 heavy chain(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human GST-conventional kinesin ATPase activity after 20 mins by malachite green assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50353788(CHEMBL1829433)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed