BDBM50361881 CHEMBL1938927

SMILES CCC(c1ccc2nc(sc2c1)-c1ccc(CN2CC(C2)C(O)=O)cc1F)c1ccccn1

InChI Key InChIKey=ADQHYBHAWCALRO-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50361881   

TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human S1P1 receptor expressed in U20S cells coexpressing eGFP assessed as receptor internalization after 1 hr by microscopy analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50361881(CHEMBL1938927)
Affinity DataEC50:  2.06E+3nMAssay Description:Agonist activity at human S1P3 receptor expressed in CHO cells coexpressing Gq/i5 protein by calcium flux assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed