BDBM50366600 CHEMBL301281

SMILES COC(=O)[C@@H]1C2CCC(C[C@@H]1OC(=O)c1ccccc1)N2

InChI Key InChIKey=AYDBLCSLKNTEJL-CLRIEMFWSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50366600   

TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50366600(CHEMBL301281)
Affinity DataKi:  540nMAssay Description:Binding affinity towards dopamine transporter using [3H]- mazindol as radioligand in rat striatal membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50366600(CHEMBL301281)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of high affinity uptake of [3H]dopamine into striatal nerve endings (synaptosomes)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rat)
Georgetown University Medical Center

Curated by ChEMBL
LigandPNGBDBM50366600(CHEMBL301281)
Affinity DataIC50:  206nMAssay Description:Inhibition of [3H]WIN-35428 binding to the dopamine transporter in rat striata.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366600(CHEMBL301281)
Affinity DataIC50:  127nMAssay Description:Inhibition of [3H]paroxetine binding to serotonin transporter in rat frontal cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50366600(CHEMBL301281)
Affinity DataIC50:  139nMAssay Description:Inhibition of [3H]nisoxetine binding to the norepinephrine transporter in rat midbrain.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed