BDBM50367879 LISINOPRIL
SMILES NCCCC[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O
InChI Key InChIKey=RLAWWYSOJDYHDC-BZSNNMDCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50367879
Affinity DataKi: 1.20nMAssay Description:Inhibition of recombinant human ACE C-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 4.80nMAssay Description:Inhibition of recombinant human ACE N-domain expressed in CHO cells using Cbz-Phe-His-Leu as substrate preincubated for 15 mins followed by substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against angiotensin I converting enzyme (ACE)Checked by AuthorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of Angiotensin I converting enzyme (ACE) in Bothrops jararaca venomMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibitory activity against Angiotensin I converting enzyme (ACE) from human blood serumMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibitory activity against angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
Affinity DataIC50: 3.98nMAssay Description:Inhibition of angiotensin I converting enzyme in silicoMore data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.90nMAssay Description:Inhibition of ACE (unknown origin) using Hippuryl-L-Histidyl-L-Leucine as substrate after 60 mins by colorimetric methodMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 281nMAssay Description:Inhibition of rabbit lung ACE using hippuryl-histidyl-leucine as substrate assessed as release of hippuric acid incubated for 10 mins prior to substr...More data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human serum ACEMore data for this Ligand-Target Pair
Affinity DataIC50: 0.100nMAssay Description:Inhibition of angiotensin converting enzyme (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin)More data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of rabbit lung ACE assessed as hydrolysis of hippuryl-histidyl-leucine to hippuric acid and histidyl-leucine after 30 minsMore data for this Ligand-Target Pair
TargetAngiotensin-converting enzyme(Rabbit)
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Csir-Indian Institute of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 318nMAssay Description:Inhibition of rabbit lung ACE assessed as hippuryl-histidyl-leucine hydrolysis after 30 mins by colorimetric methodMore data for this Ligand-Target Pair