BDBM50369395 ELIGARD::LEUPROLIDE

SMILES CCNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCC(=O)N1

InChI Key InChIKey=GFIJNRVAKGFPGQ-LIJARHBVSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50369395   

TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.800nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor the membrane fra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.5nMAssay Description:The compound was tested for the concentration to inhibit 50% of [125 I]leuprorelin binding to Leutinizing releasing hormone receptor in the membrane ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of [125I]leuprorelin binding to human recombinant LHRH receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of [125I]leuprorelin binding to monkey anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rat)
Takeda Chemical Industries

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.5nMAssay Description:Inhibition of [125I]leuprorelin binding to rat anterior pituitary LHRH receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50369395(ELIGARD | LEUPROLIDE)
Affinity DataIC50:  0.300nMAssay Description:The Compound was tested for the concentration to inhibit 50% of [125 I ]leuprorelin binding to the cloned human Leutinizing releasing hormone recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed