BDBM50374404 CHEMBL270479::JNJ-1930942

SMILES OCc1sc(Nc2ccc(F)c(c2)C(F)(F)F)nc1-c1ccncc1

InChI Key InChIKey=JBSVHWCIKVSTTH-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50374404   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50374404(CHEMBL270479 | JNJ-1930942)
Affinity DataEC50:  1.90E+3nMAssay Description:Positive allosteric modulation of human alpha7 nAChR expressed in rat GH4-C1 cells assessed as calcium flux by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50374404(CHEMBL270479 | JNJ-1930942)
Affinity DataEC50:  4.20E+3nMAssay Description:Activity at human alpha-7 nACh receptor expressed in Xenopus laevis oocyte assessed as increase in acetylcholine-induced currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed