BDBM50375309 BAY-5360::Flagyl::Flagyl 375::Flagyl ER::Flagyl i.v. rtu in plastic container::METRONIDAZOLE::Metric 21::Metro IV::Metro i.v.::MetroGel::Metrocream::Metrogel-vaginal::Metrolotion::Metrolyl::Metromidol

SMILES Cc1ncc(n1CCO)[N+]([O-])=O

InChI Key InChIKey=VAOCPAMSLUNLGC-UHFFFAOYSA-N

Data  1 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50375309   

TargetThioredoxin reductase(Entamoeba histolytica)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of Entamoeba histolytica thioredoxin reductaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50:  1.78E+5nMAssay Description:Inhibition of Cav1.2 current measured using QPatch automatic path clamp system in CHO cells expressing Cav1.2, beta-2 and alpha-2/delta-1 subunitsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol 14-alpha demethylase(Human)
Act

Curated by ChEMBL
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50375309(BAY-5360 | Flagyl | Flagyl 375 | Flagyl ER | Flagy...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed