BDBM50385169 CHEMBL2036513

SMILES Cc1ccc(COC(=O)N2CC[C@H](CNc3ncccn3)[C@H](F)C2)cc1

InChI Key InChIKey=RECBFDWSXWAXHY-IAGOWNOFSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50385169   

TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)

Curated by ChEMBL
LigandPNGBDBM50385169(CHEMBL2036513)
Affinity DataKd:  15.2nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain thalamusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)

Curated by ChEMBL
LigandPNGBDBM50385169(CHEMBL2036513)
Affinity DataKd:  5.90nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain olfactory tubercleMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)

Curated by ChEMBL
LigandPNGBDBM50385169(CHEMBL2036513)
Affinity DataKd:  9.10nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain hippocampusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)

Curated by ChEMBL
LigandPNGBDBM50385169(CHEMBL2036513)
Affinity DataKd:  9.80nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, NMDA 2B(Rat)
Institute of Biomedical Imaging (I2Bm)

Curated by ChEMBL
LigandPNGBDBM50385169(CHEMBL2036513)
Affinity DataKd:  9.30nMAssay Description:Binding affinity to NMDAR NR2B in Sprague-Dawley rat brain straitumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed