BDBM50405401 CHEMBL2051990

SMILES CC[C@@H](Cc1cnc2nc(N)nc(N)c2n1)c1ccc(cc1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

InChI Key InChIKey=FSIRXIHZBIXHKT-NHYWBVRUSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50405401   

TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataKi:  0.0120nMAssay Description:Compound was evaluated for binding affinity against Dihydrofolate reductase of L1210 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataIC50:  38nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Lactobacillus casei ATCC 7469More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Chicken)
TBA

Curated by ChEMBL
LigandPNGBDBM50405401(CHEMBL2051990)
Affinity DataIC50:  22nMAssay Description:Compound was evaluated for the inhibition of dihydrofolate reductase (DHFR) derived from Chicken liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed