BDBM50408816 CHEMBL5279890

SMILES N[C@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NC1(CCCCCCC1)C(=O)N[C@@H](CO)C(=O)N1Cc2ccccc2C[C@@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O

InChI Key InChIKey=FEUXPIABBJMKQK-YEQRNYPQSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50408816   

TargetMu-type opioid receptor(Mouse)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataKi:  1.80nMAssay Description:Antagonist activity at histamine H1 receptor in guinea pig ileum assessed as histamine-induced contractionsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataKi:  127nMAssay Description:Antagonist activity at wild type guinea pig NK3 receptor expressed in HEK293 cells assessed as inhibition of [MePhe7]NKB-induced accumulation of [3H]...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataKi:  178nMAssay Description:Antagonist activity at P2X7 receptor in human THP1 cells assessed as inhibition of BzATP-induced ethidium uptakeMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetKappa-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataEC50:  1.03E+3nMAssay Description:Antagonist activity at rat H3 receptor expressed in human SK-N-MC cells assessed as inhibition of forskolin-induced cAMP accumulation after 6 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMu-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataEC50:  19nMAssay Description:Inhibition of human recombinant triosephosphate isomerase after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetDelta-type opioid receptor(Human)
Fudan University

Curated by ChEMBL
LigandPNGBDBM50408816(CHEMBL5279890)
Affinity DataEC50:  134nMAssay Description:Antagonist activity at PAR1 expressed in CHO cells assessed as inhibition of SFLLR-NH2-induced calcium release by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed