BDBM50426287 CHEMBL2312685

SMILES NCCC[C@H](C[C@H](N)C(O)=O)C(O)=O

InChI Key InChIKey=APZMCUMLPRUVCO-RITPCOANSA-N

Data  3 KI  3 IC50  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50426287   

TargetGlutamate receptor ionotropic, kainate 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataKi:  5.53E+3nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK1(Q)1b receptor expressed in sf9 cells by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataKi:  1.02E+4nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluK3 receptor expressed in sf9 cells by liquid scintillation cou...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataKi:  8.31E+4nMAssay Description:Displacement of [3H]-(2S,4R)-4-methylglutamic acid from full length recombinant rat GluKK2(VCR) receptor expressed in sf9 cells by liquid scintillati...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu1 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50:  4.90E+3nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50:  4.89E+3nMAssay Description:Agonist activity at rat mGlu2 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 3(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human EAAT3 expressed in HEK293 cells by [3H]-D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human EAAT2 expressed in HEK293 cells by [3H]-D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetExcitatory amino acid transporter 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of human EAAT1 expressed in HEK293 cells by [3H]-D-Asp uptake assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 3(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu3 receptor expressed in HEK293 cells by [35S]GTP-gamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu4 receptor expressed in HEK293 cells assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at human mGlu7 receptor expressed in HEK293 assessed as inhibition of forskolin stimulated cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 5(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50426287(CHEMBL2312685)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat mGlu5 receptor expressed in HEK293 cells by intracellular Ca2+ mobilization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed