BDBM50453597 CHEMBL168915

SMILES Oc1ccc(O)c(CNc2ccc(O)c(c2)C(=O)Oc2cccc3ccccc23)c1

InChI Key InChIKey=OWGPFTZCQJRALJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50453597   

TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453597(CHEMBL168915)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of EGF-stimulated DNA synthesis in ER22 cells, by measuring [3H]Me-dT incorporation into ER 22 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Human)
University of Paris

Curated by ChEMBL
LigandPNGBDBM50453597(CHEMBL168915)
Affinity DataIC50:  110nMAssay Description:Inhibitory potency against protein tyrosine kinase activity associated with EGFR was evaluated using ER 22 cell membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed