BindingDB logo
myBDB logout

BDBM82370 CAS_87-00-3::Homatropine::NSC_5821

SMILES: CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1

InChI Key: InChIKey=ZTVIKZXZYLEVOL-UHFFFAOYSA-N

Data: 5 KI

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 82370   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CHRM4


(RABBIT)
BDBM82370
PNG
(CAS_87-00-3 | Homatropine | NSC_5821)
Show SMILES CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1
Show InChI InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

PubMed
25.1n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(RAT)
BDBM82370
PNG
(CAS_87-00-3 | Homatropine | NSC_5821)
Show SMILES CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1
Show InChI InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

PubMed
41.7n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM82370
PNG
(CAS_87-00-3 | Homatropine | NSC_5821)
Show SMILES CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1
Show InChI InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

PubMed
58.9n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
CHRM4


(Chick)
BDBM82370
PNG
(CAS_87-00-3 | Homatropine | NSC_5821)
Show SMILES CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1
Show InChI InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

PubMed
72.4n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair
Muscarinic receptor M2 and M3


(RAT)
BDBM82370
PNG
(CAS_87-00-3 | Homatropine | NSC_5821)
Show SMILES CN1C2CCC1CC(C2)OC(=O)C(O)c1ccccc1
Show InChI InChI=1S/C16H21NO3/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11/h2-6,12-15,18H,7-10H2,1H3
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
PDB
UniChem

Similars

PubMed
166n/an/an/an/an/an/an/an/a



Glaxo Group Research Ltd.

Curated by PDSP Ki Database




Mol Pharmacol 38: 805-15 (1990)

More data for this
Ligand-Target Pair