BDBM8839 3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(4-chlorophenyl)urea::N-[4-(4-Amino-6-methylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(4-chlorophenyl)urea::Thienopyrimidine deriv. 21

SMILES Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1

InChI Key InChIKey=PNGAHMAIVIRYPV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8839   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  96nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  29nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  1.20E+3nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  28.8nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetAngiopoietin-1 receptor(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  95.5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8839(3-(4-{4-amino-6-methylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50:  29nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed