BDBM92673 Isoquinolinesulfonamide, CKI-6

SMILES NCCNS(=O)(=O)c1cccc2ccncc12

InChI Key InChIKey=QPNMAJFDZKCKTR-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 92673   

TargetCasein kinase I isoform alpha(Human)
Nagoya University School of Medicine

LigandPNGBDBM92673(Isoquinolinesulfonamide, CKI-6)
Affinity DataIC50:  5.00E+4nMpH: 7.4 T: 30°CAssay Description:Casein kinase activities were determined under the conditions as described by Huang et al (1982).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCasein kinase II subunit alpha(Human)
Nagoya University School of Medicine

LigandPNGBDBM92673(Isoquinolinesulfonamide, CKI-6)
Affinity DataIC50: >3.00E+5nMpH: 7.4 T: 30°CAssay Description:Casein kinase activities were determined under the conditions as described by Huang et al (1982).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCalcium/calmodulin-dependent protein kinase II inhibitor 2(Bovine)
Nagoya University School of Medicine

LigandPNGBDBM92673(Isoquinolinesulfonamide, CKI-6)
Affinity DataIC50:  8.40E+5nMpH: 7.4 T: 30°CAssay Description:Casein kinase activities were determined under the conditions as described by Huang et al (1982).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetcAMP-dependent protein kinase type I-alpha regulatory subunit(Bovine)
Nagoya University School of Medicine

LigandPNGBDBM92673(Isoquinolinesulfonamide, CKI-6)
Affinity DataIC50: >1.00E+6nMpH: 7.4 T: 30°CAssay Description:Casein kinase activities were determined under the conditions as described by Huang et al (1982).More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein kinase C alpha type(Human)
Nagoya University School of Medicine

LigandPNGBDBM92673(Isoquinolinesulfonamide, CKI-6)
Affinity DataIC50: >1.00E+6nMpH: 7.4 T: 30°CAssay Description:Casein kinase activities were determined under the conditions as described by Huang et al (1982).More data for this Ligand-Target Pair
In DepthDetails PubMed