BDBM50062599 3,5-Dimethyl-adamantan-1-ylamine::CHEMBL807::MEMANTINE::Namenda::US10214478, Compound memantine

SMILES: CC12CC3CC(C)(C1)CC(N)(C3)C2

InChI Key: InChIKey=BUGYDGFZZOZRHP-UHFFFAOYSA-N

Data: 12 KI  14 IC50  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 27 hits for monomerid = 50062599   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum - University of Bologna Curated by ChEMBL					Assay Description Antagonist activity at GluN1a/GluN2A (unknown origin) expressed in Xenopus laevis oocytes at -60 mV holding potential by voltage clamp method				Eur J Med Chem 180: 111-120 (2019) Article DOI: 10.1016/j.ejmech.2019.07.011
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.78E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.73E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
					More data for this Ligand-Target Pair
Ionotropic glutamate receptor subunit Delta2 (Xenopus)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB UniProtKB/TrEMBL GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
State University of New York Curated by PDSP Ki Database									J Pharmacol Exp Ther 305: 740-8 (2003) Article DOI: 10.1124/jpet.102.045799 BindingDB Entry DOI: 10.7270/Q2N878C5
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.36E+3	n/a	n/a	n/a	n/a	7.6	n/a
Xavier University of Louisiana Curated by ChEMBL					Assay Description Antagonist activity at NR1/NR2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced cur...				Bioorg Med Chem 22: 1983-92 (2014) Article DOI: 10.1016/j.bmc.2014.02.049 BindingDB Entry DOI: 10.7270/Q2N29ZGG
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Inhibition of NMDA NR1/NR2B receptor (unknown origin) expressed in xenopus oocytes assessed as inhibition of NMDA and glycine-induced current respons...				J Med Chem 51: 4381-4 (2008) Article DOI: 10.1021/jm800577j BindingDB Entry DOI: 10.7270/Q21G0M23
					More data for this Ligand-Target Pair
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of dexamethasone-induced human NR1-1a/NR2B receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L13-E6 cells assesse...				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of dexamethasone-induced human NR1-1a/NR2A receptor-mediated excitotoxicity in (S)-glutamate/glycine-stimulated mouse L12-G10 cells assess...				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electrophorus electricus (Electric eel))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of electric eel AChE by modified Ellman's method				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
Cholinesterase (Equus caballus (Horse))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich-Schiller-Universitat Jena Curated by ChEMBL					Assay Description Inhibition of equine serum BChE by modified Ellman's method				J Med Chem 53: 3611-7 (2010) Article DOI: 10.1021/jm1000024 BindingDB Entry DOI: 10.7270/Q2SJ1KS0
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2C (Rattus norvegicus (Rat))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Compound with the N-methyl-D-aspartate glutamate receptor blocking activity				J Med Chem 42: 1481-500 (1999) Article DOI: 10.1021/jm9805034 BindingDB Entry DOI: 10.7270/Q2HX1DCV
					More data for this Ligand-Target Pair
Solute carrier family 22 member 1 (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of 4-(4-(dimethylamino)styryl)-N-methylpyridinium uptake at human OCT1 expressed in HEK293 cells by confocal microscopy				J Med Chem 51: 5932-42 (2008) Article DOI: 10.1021/jm8003152 BindingDB Entry DOI: 10.7270/Q23779MD
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Displacement of [3H]Ifenprodil from NMDAR-2B in Sprague-Dawley rat frontal cortex homogenates after 2 hrs by liquid scintillation counting				J Med Chem 55: 9708-21 (2012) Article DOI: 10.1021/jm3009458 BindingDB Entry DOI: 10.7270/Q2VQ33TR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	US Patent	n/a	n/a	n/a	n/a	2.72E+3	n/a	n/a	n/a	n/a
TBA US Patent					Assay Description Isolated primary cerebellum granule cells of infant rats were inoculated in 96-well plates with 1.2×105/well by using 10% FBS+25 mM KCl+2 mM Glutamin...				US Patent US10214478 (2019) BindingDB Entry DOI: 10.7270/Q2V12745
					More data for this Ligand-Target Pair
Bile salt export pump (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...				Drug Metab Dispos 40: 2332-41 (2012) Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 2/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima University Curated by ChEMBL					Assay Description Antagonist activity at rat brain GluN1/GluN2B receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channe...				Bioorg Med Chem 26: 603-608 (2018) Article DOI: 10.1016/j.bmc.2017.12.021 BindingDB Entry DOI: 10.7270/Q218393W
					More data for this Ligand-Target Pair
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hiroshima University Curated by ChEMBL					Assay Description Antagonist activity at rat brain GluN1/GluN2A receptor expressed in Xenopus laevis oocytes assessed as inhibition of glutamate/glycine-induced channe...				Bioorg Med Chem 26: 603-608 (2018) Article DOI: 10.1016/j.bmc.2017.12.021 BindingDB Entry DOI: 10.7270/Q218393W
					More data for this Ligand-Target Pair
GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Barcelona Curated by ChEMBL					Assay Description Inhibition of recombinant GluN1/GluN2B receptor (unknown origin) expressed in HEK293 cells by patch-clamp method				Eur J Med Chem 180: 613-626 (2019) Article DOI: 10.1016/j.ejmech.2019.07.051
					More data for this Ligand-Target Pair
NR1/NR2A (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Antagonist activity at recombinant GluN1/GluN2A receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as inhibition of glycine/gluta...				Bioorg Med Chem Lett 23: 3901-4 (2013) Article DOI: 10.1016/j.bmcl.2013.04.063 BindingDB Entry DOI: 10.7270/Q2JM2DK4
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GluN1/GluN2B NMDA receptor (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Antagonist activity at recombinant NR1/NR2B receptor expressed in Xenopus laevis oocytes				Bioorg Med Chem Lett 17: 4729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.06.069 BindingDB Entry DOI: 10.7270/Q23F4SFW
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NR1/NR2A (Homo sapiens (Human))	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	911	n/a	n/a	n/a	n/a	n/a	n/a
Chiba University Curated by ChEMBL					Assay Description Antagonist activity at recombinant NR1/NR2A receptor expressed in Xenopus laevis oocytes				Bioorg Med Chem Lett 17: 4729-32 (2007) Article DOI: 10.1016/j.bmcl.2007.06.069 BindingDB Entry DOI: 10.7270/Q23F4SFW
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 1 (RAT)	BDBM50062599 (3,5-Dimethyl-adamantan-1-ylamine | CHEMBL807 | MEM...) Show SMILES CC12CC3CC(C)(C1)CC(N)(C3)C2 Show InChI InChI=1S/C12H21N/c1-10-3-9-4-11(2,6-10)8-12(13,5-9)7-10/h9H,3-8,13H2,1-2H3	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar	Purchase CHEBI CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	433	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merz Co. GmbH & Co. Curated by PDSP Ki Database									Neuropharmacology 34: 533-40 (1995) Article DOI: 10.1016/0028-3908(95)00017-z BindingDB Entry DOI: 10.7270/Q2M9075F
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