Found 6 hits for monomerid = 50080153 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Voltage-gated calcium channel alpha2/delta subunit 1
(Mus musculus) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
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Patents
Similars
| Article PubMed
| 120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]L-leucine from alpha2delta containing calcium channel in murine brain |
Bioorg Med Chem Lett 16: 1138-41 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.108 BindingDB Entry DOI: 10.7270/Q2XS5TXV |
More data for this Ligand-Target Pair | |
Bile salt export pump
(Homo sapiens (Human)) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
Reactome pathway
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Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-... |
Drug Metab Dispos 40: 2332-41 (2012)
Article DOI: 10.1124/dmd.112.047068 BindingDB Entry DOI: 10.7270/Q2ZP488M |
More data for this Ligand-Target Pair | |
Voltage-dependent calcium channel alpha2delta subunit
(Sus scrofa) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
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UniProtKB/TrEMBL
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Patents
Similars
| Article PubMed
| n/a | n/a | 70 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]gabapentin from alpha-2delta calcium channel in pig brain membrane |
Bioorg Med Chem Lett 16: 2333-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.05.016 BindingDB Entry DOI: 10.7270/Q2CV4JJZ |
More data for this Ligand-Target Pair | |
Voltage-gated calcium channel alpha2/delta subunit 1
(Rattus norvegicus) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
Reactome pathway
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CHEBI CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description Inhibition of potassium-evoked [3H]norepinephrine release from rat neocortex |
Bioorg Med Chem Lett 16: 2333-6 (2006)
Article DOI: 10.1016/j.bmcl.2005.05.016 BindingDB Entry DOI: 10.7270/Q2CV4JJZ |
More data for this Ligand-Target Pair | |
Voltage-dependent calcium channel subunit alpha-2/delta-1
(Homo sapiens (Human)) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar
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CHEBI CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
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| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description Binding affinity towards alpha2-delta subunit of a voltage gated calcium channel using [3H]-gabapentin in human brain membrane (A710 membrane) |
Bioorg Med Chem Lett 14: 1913-6 (2004)
Article DOI: 10.1016/j.bmcl.2004.01.087 BindingDB Entry DOI: 10.7270/Q2HQ3ZBQ |
More data for this Ligand-Target Pair | |
Voltage-dependent calcium channel alpha2delta subunit
(Sus scrofa) | BDBM50080153
((1-Aminomethyl-cyclohexyl)-acetic acid | 2-(1-(ami...)Show InChI InChI=1S/C9H17NO2/c10-7-9(6-8(11)12)4-2-1-3-5-9/h1-7,10H2,(H,11,12) | PDB
KEGG
UniProtKB/TrEMBL
GoogleScholar
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CHEBI CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc
Curated by ChEMBL
| Assay Description Displacement of [3H]gabapentin from calcium channel alpha2delta in pig cerebral cortex membrane after 30 mins |
Bioorg Med Chem Lett 20: 362-5 (2010)
Article DOI: 10.1016/j.bmcl.2009.10.089 BindingDB Entry DOI: 10.7270/Q2XD11S7 |
More data for this Ligand-Target Pair | |