Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 8642
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410051(US10370368, Example 1)
Affinity DataEC50:  6nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410055(US10370368, Example 2 | US10370368, Example 3)
Affinity DataEC50:  6nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410055(US10370368, Example 2 | US10370368, Example 3)
Affinity DataEC50:  78nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410087(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  8nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410088(US10370368, Example 5)
Affinity DataEC50:  5nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410094(N-(Cyclopropylsulfonyl)-2-((3R,4S or 3S,4R)-4-hydr...)
Affinity DataEC50:  391nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410090(N-(tert-Butylsulfonyl)-2-((rac-trans)-4-hydroxy-3-...)
Affinity DataEC50:  5nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410091(N-(Cyclopropylsulfonyl)-2-((rac-trans)-4-hydroxy-3...)
Affinity DataEC50:  12nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410092(N-(Cyclopropylsulfonyl)-2-((rac-trans)-4-hydroxy-3...)
Affinity DataEC50:  9nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410092(N-(Cyclopropylsulfonyl)-2-((rac-trans)-4-hydroxy-3...)
Affinity DataEC50:  6nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLeukotriene B4 receptor 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM410089(US10370368, Example 6)
Affinity DataEC50:  128nMAssay Description:The ability of compounds to antagonize the human BLT1 receptor was determined using a kit to measure changes in intracellular cyclic AMP levels (cAMP...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent