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Found 1406 with Last Name = 'laria' and Initial = 'jc'
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128311(US8796284, 93)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128297(US8796284, 4)
Affinity DataKi:  6nM ΔG°:  -46.9kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128307(US8796284, 38)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128310(US8796284, 48)
Affinity DataKi:  7nM ΔG°:  -46.5kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128306(US8796284, 36)
Affinity DataKi:  8nM ΔG°:  -46.2kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101261(US8524717, 16)
Affinity DataKi:  9nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101302(CHEMBL3108900 | US8524717, 57)
Affinity DataKi:  9nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128305(US8796284, 29)
Affinity DataKi:  10nM ΔG°:  -45.7kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128296(US8796284, 3)
Affinity DataKi:  11nM ΔG°:  -45.4kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128311(US8796284, 93)
Affinity DataKi:  12nM ΔG°:  -47.0kJ/moleT: 2°CAssay Description:hese assays were performed at adenosine receptors transfected using a cAMP enzymeimmunoassay kit (Amersham Biosciences). CHO-A2A cells were seeded (1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128295(US8796284, 1)
Affinity DataKi:  12nM ΔG°:  -45.2kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375232(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)...)
Affinity DataKi:  12nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375233(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-4-yl)p...)
Affinity DataKi:  13nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128303(US8796284, 20)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128298(US8796284, 5)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128308(US8796284, 44)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101276(US8524717, 31)
Affinity DataKi:  15nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128304(US8796284, 24)
Affinity DataKi:  16nM ΔG°:  -44.5kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128309(US8796284, 46)
Affinity DataKi:  17nM ΔG°:  -44.3kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101278(US8524717, 33)
Affinity DataKi:  17nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101273(US8524717, 28)
Affinity DataKi:  18nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101305(US8524717, 60)
Affinity DataKi:  18nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128299(US8796284, 8)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128301(US8796284, 10)
Affinity DataKi:  21nM ΔG°:  -43.8kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101300(US8524717, 55)
Affinity DataKi:  21nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101274(US8524717, 29)
Affinity DataKi:  22nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375229(3-chloro-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)...)
Affinity DataKi:  23.9nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101289(US8524717, 44)
Affinity DataKi:  24nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101291(US8524717, 46)
Affinity DataKi:  24nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375234(3-chloro-5-(3-fluoropyridin-4-yl)-6-(6-methoxypyri...)
Affinity DataKi:  24nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101304(US8524717, 59)
Affinity DataKi:  25nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101283(US8524717, 38)
Affinity DataKi:  25nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101277(US8524717, 32)
Affinity DataKi:  25nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128295(US8796284, 1)
Affinity DataKi:  25nM ΔG°:  -45.1kJ/moleT: 2°CAssay Description:hese assays were performed at adenosine receptors transfected using a cAMP enzymeimmunoassay kit (Amersham Biosciences). CHO-A2A cells were seeded (1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101290(US8524717, 45)
Affinity DataKi:  26nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101285(US8524717, 40)
Affinity DataKi:  26nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101286(US8524717, 41)
Affinity DataKi:  27nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101293(US8524717, 48)
Affinity DataKi:  29nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101284(US8524717, 39)
Affinity DataKi:  30nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101271(US8524717, 26)
Affinity DataKi:  30nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128300(US8796284, 9)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375227(3-chloro-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-...)
Affinity DataKi:  34.5nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM128302(US8796284, 13)
Affinity DataKi:  35nM ΔG°:  -42.6kJ/moleT: 2°CAssay Description:Competition assays were carried out by incubation of membranes from hA1 receptors transfected to CHO cells, [3H]-DPCPX as radioligand, buffer (HEPES ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375230(3-bromo-5-(3-fluoropyridin-4-yl)-6-(pyridin-3-yl)p...)
Affinity DataKi:  37nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101297(US8524717, 52)
Affinity DataKi:  40nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101257(US8524717, 12)
Affinity DataKi:  40nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101287(US8524717, 42)
Affinity DataKi:  42nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101282(US8524717, 37)
Affinity DataKi:  43nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
Palobiofarma

US Patent
LigandPNGBDBM375228(3-bromo-6-(pyridin-3-yl)-5-(pyridin-4-yl)pyridin-2...)
Affinity DataKi:  46.1nMAssay Description:The binding assay for adenosine A2B receptor subtype was carried out on human recombinant source (HEK-293 cells) and [3H]DPCPX as radioligand, accord...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
Oryzon Genomics

US Patent
LigandPNGBDBM101303(US8524717, 58)
Affinity DataKi:  47nMAssay Description:Biological assay using monoamine oxidase or LSD1.More data for this Ligand-Target Pair
In DepthDetails US Patent
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