BDBM50131078 3-formylchromones::4-Oxo-4H-chromene-3-carbaldehyde::CHEMBL86905

SMILES O=Cc1coc2ccccc2c1=O

InChI Key InChIKey=FSMYWBQIMDSGQP-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50131078   

TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataKi:  580nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysSMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Klebsiella pneumoniae)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataKi:  7.60E+4nMAssay Description:Time-dependent inhibition of wild type Klebsiella pneumoniae 6xHis-tagged metallo-beta-lactamase NDM-1 expressed in Escherichia coli BL21 (DE3)pLysS ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine phosphorylase(Escherichia coli)
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of Escherichia coli thymidine phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  2.35E+4nMAssay Description:Inhibition of recombinant human MAO-B assessed as inhibition of kynuramine to 4-hydroxyquinoline conversion after 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
North-West University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  2.89E+4nMAssay Description:Inhibition of recombinant human MAO-A assessed as inhibition of kynuramine to 4-hydroxyquinoline conversion after 20 mins by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Inha University

Curated by ChEMBL
LigandPNGBDBM50131078(3-formylchromones | 4-Oxo-4H-chromene-3-carbaldehy...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of human Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed