BDBM35440 ALLOPURINOL::MLS000069453::SMR000059083::cid_2094
SMILES O=c1[nH]cnc2n[nH]cc12
InChI Key InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 42 hits for monomerid = 35440
Affinity DataKi: 7.00E+3nMAssay Description:Inhibitory activity against Xanthine OxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of bovine xanthine oxidase assessed as uric acid formation using xanthine as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.43E+3nMpH: 7.8 T: 25°CAssay Description:The effect of 2-styrylchromone 1-3 on xanthine oxidase activity was evaluated by measuring the formation of uric acid from xanthine in a double beam ...More data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+3nMpH: 7.6 T: 25°CAssay Description:Bovine milk XO activity was assayed spectrophotometrically by measuring the uric acid formation at 293 nm using a UV-visible spectrophotometer at 25&...More data for this Ligand-Target Pair
Affinity DataIC50: 7.50E+3nMpH: 7.6 T: 25°CAssay Description:Inhibition of xanthine oxidase (XO) by each isolated phenolics was measured by following the decrease in the uric acid formation at 293nm at 25°...More data for this Ligand-Target Pair
Affinity DataIC50: 3.16E+4nMpH: 7.5 T: 25°CAssay Description:The reaction mixture contained 1.5 mL of 50 mM potassium phosphate buffer (pH 7.5), 1 mL test sample solutions (5, 10, 25, 50, and 100 µM) was d...More data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibitory activity against Xanthine OxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:In vitro inhibitory concentration against Xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 9.82E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 7.82E+3nMAssay Description:Inhibition of human xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as uric acid formation by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of xanthine oxidase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.18E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of superoxide generationMore data for this Ligand-Target Pair
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as decrease of uric acid generationMore data for this Ligand-Target Pair
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of xanthine oxidase (unknown origin) assessed as formation of formazan at 16 ug/ml after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of cow milk xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of bovine milk XOR-mediated uric acid formation after 15 mins by spectrophotometerMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of bovine milk xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 753nMAssay Description:Inhibition of rat liver xanthine oxidase by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of bovine Xanthine oxidase assessed as decrease in uric acid production preincubated at 293 nM of compound for 5 mins by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of xanthine oxidase activity assessed as uric acid formation pretreated for 15 mins before substrate addition measured after 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of bovine milk xanthine oxidase assessed as decrease of uric acid formation preincubated for 5 mins by UV-visible spectrophotometric analy...More data for this Ligand-Target Pair
Affinity DataIC50: 3.49E+4nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of bovine milk xanthine oxidase using xanthine as substrate assessed as decrease in uric acid formation preincubated for 5 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of bovine xanthine oxidase using xanthine as substrate measured for 6 mins at 25 degC by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of Wistar albino rat xanthine oxidase isolated from liver using xanthine as substrate incubated for 15 mins prior to substrate addition by...More data for this Ligand-Target Pair
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of bovine milk XO assessed as decrease in uric acid formation after 5 mins by UV-spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of bovine xanthine oxidase-mediated uric acid production after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetPurine nucleoside phosphorylase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Pontifical Catholic University of Rio Grande Do Sul
Curated by ChEMBL
Pontifical Catholic University of Rio Grande Do Sul
Curated by ChEMBL
Affinity DataKd: 1.00E+6nMAssay Description:Binding affinity to Mycobacterium tuberculosis purine nucleoside phosphorylase by spectrophotometric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of rat liver xanthine oxidase after 2 hrs by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of xanthine oxidaseMore data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of xanthine oxidase assessed as decrease in uric acid production by spectrophotometryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.19E+3nMAssay Description:Inhibition of xanthine oxidase using xanthine as substrate at 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 1(Human)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: >5.00E+4nMpH: 7.0 T: 22°CAssay Description:The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...More data for this Ligand-Target Pair
TargetDual specificity protein phosphatase 6(Rat)
University of Pittsburgh
Curated by PubChem BioAssay
University of Pittsburgh
Curated by PubChem BioAssay
Affinity DataIC50: >5.00E+4nMAssay Description:The in vitro MKP-3 Phosphatase dose response hit/probe assessment assay has been developed and run at the University of Pittsburgh Molecular Screenin...More data for this Ligand-Target Pair