BDBM50338972 5,7-Dimethoxy-2-phenyl-chromen-4-one::5,7-dimethoxy-2-phenyl-4H-chromen-4-one::CHEMBL275391::Chrysin-dimethylether::cid_88881

SMILES COc1cc(OC)c2c(c1)oc(cc2=O)-c1ccccc1

InChI Key InChIKey=JRFZSUMZAUHNSL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50338972   

TargetNuclear receptor subfamily 0 group B member 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50338972(5,7-Dimethoxy-2-phenyl-chromen-4-one | 5,7-dimetho...)
Affinity DataIC50: >6.76E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetSteroidogenic factor 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50338972(5,7-Dimethoxy-2-phenyl-chromen-4-one | 5,7-dimetho...)
Affinity DataIC50: >6.76E+4nMMore data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetUrease subunit beta(Helicobacter pylori (strain ATCC 700392 / 26695) (...)
Jishou University

Curated by ChEMBL
LigandPNGBDBM50338972(5,7-Dimethoxy-2-phenyl-chromen-4-one | 5,7-dimetho...)
Affinity DataIC50:  2.19E+6nMAssay Description:Inhibition of Helicobacter pylori ATCC 43504 urease-mediated ammonia production preincubated for 1.5 hrs by indophenol methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338972(5,7-Dimethoxy-2-phenyl-chromen-4-one | 5,7-dimetho...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50338972(5,7-Dimethoxy-2-phenyl-chromen-4-one | 5,7-dimetho...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of BCRP expressed in MDCK cells using Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed