BDBM50406795 Cozaar::LOSARTAN POTASSIUM
SMILES CCCCc1nc(Cl)c(CO)n1Cc1ccc(cc1)-c1ccccc1-c1nn[n-]n1
InChI Key InChIKey=MDMTUGIZSFHDIC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 13 hits for monomerid = 50406795
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataKi: 9nMAssay Description:In vitro antagonistic potency against angiotensin II receptor using [125I]- Sar,Ile8-angiotensin II as the radioligand in rat adrenal cortical membra...More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Compound was tested in vitro for the ability to displace the specific binding of [125I]-A II from receptors in rat liver membrane(type 1 receptor)More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:In vitro binding affinity of compound against angiotensin II AT-2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:In vitro binding affinity of compound against Angiotensin II receptor, type 1More data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor B(Rat)
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 1.5nMAssay Description:Binding affinity against AT1 receptor in the presence of 0.01% BSAMore data for this Ligand-Target Pair
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of specific binding of [125 I ] Angiotensin-II (0.2 nM) to bovine adrenal cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 8.20nMAssay Description:In vitro binding affinity determined against angiotensin II AT1 receptor in rat adrenal cortex preparationMore data for this Ligand-Target Pair
TargetType-1 angiotensin II receptor A/Type-1 angiotensin II receptor B/Type-2 angiotensin II receptor(Rat)TBA
Affinity DataIC50: 19nMAssay Description:Angiotensin II receptor antagonist activity was determined by 50% inhibition of specific binding of [3H]angiotensin II (2 nM) to rat adrenal cortical...More data for this Ligand-Target Pair
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
Affinity DataIC50: 8.53E+3nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro binding affinity determined against angiotensin II AT2 receptor in rat adrenal medulla preparationMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:In vitro inhibition of the specific binding of [125I]-angiotensin II to a guinea pig adrenal membrane preparationMore data for this Ligand-Target Pair