BDBM31775 Amudane::Fulvicin::Grisefuline::Griseofulvin

SMILES COC1=CC(=O)C[C@@H](C)[C@]11Oc2c(C1=O)c(OC)cc(OC)c2Cl

InChI Key InChIKey=DDUHZTYCFQRHIY-RBHXEPJQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 31775   

TargetHeme oxygenase 1(Rat)
Queen'S University

LigandPNGBDBM31775(Amudane | Fulvicin | Grisefuline | Griseofulvin)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 37°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetSolute carrier family 22 member 1(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM31775(Amudane | Fulvicin | Grisefuline | Griseofulvin)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of human OCT1 expressed in HEK293 cells assessed as decrease in uptake of ASP+ after 2 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetLanosterol 14-alpha demethylase(Human)
Act

Curated by ChEMBL
LigandPNGBDBM31775(Amudane | Fulvicin | Grisefuline | Griseofulvin)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetHeme oxygenase 2(Rat)
Queen'S University

LigandPNGBDBM31775(Amudane | Fulvicin | Grisefuline | Griseofulvin)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 37°CAssay Description:HO activity in rat spleen (HO-1) and brain (HO-2) microsomal fractions was determined by the quantitation of CO formed from the degradation of methem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed