BDBM86422 CAS_61869-08-7::NSC_43815::PAROXETINE::US9873683, Paroxetine

SMILES Fc1ccc(cc1)C1CCNCC1COc1ccc2OCOc2c1

InChI Key InChIKey=AHOUBRCZNHFOSL-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 10 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86422   

TargetSodium-dependent serotonin transporter(Mouse)
National Institutes of Health

Curated by PDSP K_i Database

LigandBDBM86422(CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...)Copy SMILESCopy InChI

Affinity DataKi:  4.70nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMedPDB3D Structure (crystal)
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TargetSodium-dependent dopamine transporter(Rat)
University of Tours

Curated by PDSP K_i Database

LigandBDBM86422(CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...)Copy SMILESCopy InChI

Affinity DataKi:  1.00E+3nMMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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TargetP2X purinoceptor 4(Human)
Nippon Chemiphar

US Patent

LigandBDBM86422(CAS_61869-08-7 | NSC_43815 | PAROXETINE | US987368...)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+3nMAssay Description:The 1321N1 cells stably expressing human P2X4 receptor were seeded on a 96-well plate, cultured under the conditions of 37° C. and 5% CO2 for 24 hour...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
DrugBankantibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPDBPatentsSimilars

In DepthDetails US Patent

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Copy reaction URL