BDBM50421840 MDL-18962::PLOMESTANE

SMILES C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34CC#C)[C@@H]1CCC2=O

InChI Key InChIKey=JKPDEYAOCSQBSZ-OEUJLIAZSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50421840   

TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  4nMAssay Description:In vitro inhibition of Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  6.20nMAssay Description:Binding affinity(KI) for formation of reversible enzyme-ligand complex with human placental aromatase (PL2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataKi:  15nMAssay Description:Binding affinity for human placental microsome Cytochrome P450 19A1 by nonlinear regression analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Janssen Research Foundation

Curated by ChEMBL
LigandPNGBDBM50421840(MDL-18962 | PLOMESTANE)
Affinity DataIC50:  56nMAssay Description:Inhibition of human placental microsome Cytochrome P450 19A1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed