BDBM50295572 5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-diol::5-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,3-diol, 6::Alupent::CHEMBL776::METAPROTERENOL::Orciprenaline::Prometa::[2-(3,5-Dihydroxy-phenyl)-2-hydroxy-ethyl]-isopropyl-ammonium::[2-(3,5-Dihydroxy-phenyl)-2-hydroxy-ethyl]-isopropyl-ammonium (orciprenaline)

SMILES CC(C)NCC(O)c1cc(O)cc(O)c1

InChI Key InChIKey=LMOINURANNBYCM-UHFFFAOYSA-N

Data  1 IC50  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295572   

TargetBeta-adrenergic receptor kinase 1(Human)
Merck Sharp and Dohme Research Laboratories

LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  1.30E+4nMAssay Description:The binding of ligands to wild-type beta-AR was measured by competition with 35 pM 125I-CYP.More data for this Ligand-Target Pair
In DepthDetails PubMed

TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  4.81E+3nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-2 adrenergic receptor(Human)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  501nMAssay Description:Binding affinity to beta-2 adrenergic receptor (unknown origin) at 1 to 10000 nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank


TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  4.27E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibitory affect against rabbit thymus thymidine kinase and represented as molt/4F kinase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBeta-2 adrenergic receptor(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50295572(5-(1-Hydroxy-2-isopropylamino-ethyl)-benzene-1,3-d...)
Affinity DataKd:  9.12E+3nMAssay Description:Affinity for cow beta-2 adrenergic receptor by measuring displacement (-)-[3H]dihydroalprenolol (DHA)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed