BDBM50339190 CHEMBL443683::telomestatin

SMILES Cc1oc2nc1c1nc(co1)c1nc(co1)c1nc(co1)c1nc(co1)c1nc(co1)c1SCc(n1)c1[nH]c2c(C)o1

InChI Key InChIKey=VYWLOEZWRJWFGS-UKDGSBPWSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50339190   

TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human Telomerase activity in cell free system by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  5.01E+6nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50339190(CHEMBL443683 | telomestatin)
Affinity DataIC50:  900nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed