BDBM50339190 CHEMBL443683::telomestatin
SMILES Cc1oc2nc1c1nc(co1)c1nc(co1)c1nc(co1)c1nc(co1)c1nc(co1)c1SCc(n1)c1[nH]c2c(C)o1
InChI Key InChIKey=VYWLOEZWRJWFGS-UKDGSBPWSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50339190
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human Telomerase activity in cell free system by TRAP assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 0.640nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated before telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells treated after telomerase elongation by telomeric repeat amplification protocol assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 5.01E+6nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer TS by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of human telomerase expressed in in HEK293T cells in presence of primer (T2AG3)4 by primer extension assayMore data for this Ligand-Target Pair
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
Sapienza University Of Rome
Curated by ChEMBL
Sapienza University Of Rome
Curated by ChEMBL
Affinity DataIC50: 900nMAssay Description:Inhibition of human telomerase expressed in HEK293T cells in presence of primer (T2AG3)3 by primer extension assayMore data for this Ligand-Target Pair