BDBM39349 MLS000028526::N-methyl-N-(3-methylphenyl)carbamothioic acid O-(2-naphthalenyl) ester::N-methyl-N-(m-tolyl)thiocarbamic acid O-(2-naphthyl) ester::O-naphthalen-2-yl N-methyl-N-(3-methylphenyl)carbamothioate::SMR000058288::TOLNAFTATE::cid_5510

SMILES CN(C(=S)Oc1ccc2ccccc2c1)c1cccc(C)c1

InChI Key InChIKey=FUSNMLFNXJSCDI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 39349   

TargetGenome polyprotein(WNV)
University of Pittsburgh

Curated by PubChem BioAssay
LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: >5.00E+4nMAssay Description:The HTS assay to identify Inhibitors of West Nile Virus (WNV) NS2bNS3 Proteinase was proposed by Dr Alex Strongin of the Burnham Institute XO1-MH0776...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetLanosterol 14-alpha demethylase(Human)
Act

Curated by ChEMBL
LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: <1.03E+4nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM39349(MLS000028526 | N-methyl-N-(3-methylphenyl)carbamot...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed