BDBM34179 CHEMBL1068::MLS000084586::OXCARBAZEPINE::SMR000048684::Trileptal::cid_34312

SMILES NC(=O)N1c2ccccc2CC(=O)c2ccccc12

InChI Key InChIKey=CTRLABGOLIVAIY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 34179   

TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.00E+5nMpH: 7.0 T: 23°CAssay Description:The aim is to identify chemical probes of Bfl-1 through a fluorescence polarization assay (FPA) using FITC-Bid BH3 peptide. 1) Dose-response curves c...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetBcl-2-related protein A1(Mouse)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.00E+5nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay

TargetP2X purinoceptor 4(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human P2X4 receptor expressed in human 1321N1 cells assessed as inhibition of ATP-induced cytosolic calcium influx preincubate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: <1.61E+5nMAssay Description:Displacement of [3H]BTX from voltage-gated sodium channel of rat cortical synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP3 overexpressed in Sf9 insect cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP4 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetBile salt export pump(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human BSEP overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-taurocholate in presence of ATP measured after 15 to ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM34179(CHEMBL1068 | MLS000084586 | OXCARBAZEPINE | SMR000...)
Affinity DataIC50: >1.33E+5nMAssay Description:Inhibition of human MRP2 overexpressed in Sf9 cell membrane vesicles assessed as uptake of [3H]-estradiol-17beta-D-glucuronide in presence of ATP and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed