BDBM50236983 2-Hydroxy-cyclohepta-2,4,6-trienone::2-hydroxycyclohepta-2,4,6-trienone::CHEMBL121188::tropolone

SMILES Oc1cccccc1=O

InChI Key InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N

Data  9 IC50

PDB links: 5 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50236983   

TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  1.46E+5nMAssay Description:Inhibition of human recombinant MMP2 after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mushroom tyrosinase after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDopamine beta-hydroxylase(Homo sapiens (Human))
City University Of New York

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of dopamine beta-oxygenase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarboxypeptidase A1(Bos taurus (bovine))
Osaka Organic Chemical Industry

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  2.73E+3nMAssay Description:Inhibition of Bos taurus (bovine) pancrease carboxypeptidase A after 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Osaka Organic Chemical Industry

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  7.11E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin after 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase ColG(Clostridium histolyticum)
Osaka Organic Chemical Industry

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  4.68E+4nMAssay Description:Inhibition of Clostridium histolyticum collagenase after 15 minMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50236983(2-Hydroxy-cyclohepta-2,4,6-trienone | 2-hydroxycyc...)
Affinity DataIC50:  400nMAssay Description:Inhibition of mushroom tyrosinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed