BDBM244216 US9546173, cmpd 155::n-(1-benzylpyrrolidin-3-yl)-5,5-dimethyl-2-(phenylamino)-5h-pyrrolo[3,4-d]pyrimidine-6(7h)-carboxamide

SMILES CC1(C)N(Cc2nc(Nc3ccccc3)ncc12)C(=O)NC1CCN(Cc2ccccc2)C1

InChI Key InChIKey=RAPBSGQZKKKEHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 244216   

TargetMitogen-activated protein kinase 1(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 244216BDBM244216(n-(1-benzylpyrrolidin-3-yl)-5,5-dimethyl-2-(phenyl...)
Affinity DataIC50: 969nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent

TargetRibosomal protein S6 kinase alpha-3(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 244216BDBM244216(n-(1-benzylpyrrolidin-3-yl)-5,5-dimethyl-2-(phenyl...)
Affinity DataIC50: 1.91E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/19/2018
Entry Details
US Patent