BDBM295248 Rac-3-(6-amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-3-yl)-N-(2-hydroxypropyl)-4-methylbenzenesulfonamide::US10112926, Example 108

SMILES CC(O)CNS(=O)(=O)c1ccc(C)c(c1)-c1cnc(N)c(c1)-c1nc(C)no1

InChI Key InChIKey=OXKACKLTXZOHOG-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 295248   

LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 41nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 140nMpH: 7.5Assay Description:The TR-FRET Adapta Universal Kinase Assay Kit was purchased from Invitrogen Corporation (Carlsbad, Calif., USA) (Cat. No. PV5099). The kit contains t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 640nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

TargetPhosphatidylinositol 4-kinase beta(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 5.90E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 7.30E+3nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The luminescence-based ATP detection reagent KinaseGlo was obtained from Promega, (Cat. No. V6714, Lot No. 236161) through Catalys, Wallisellen, Swit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent

TargetSerine/threonine-protein kinase mTOR(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 295248BDBM295248(US10112926, Example 108 | Rac-3-(6-amino-5-(3-meth...)
Affinity DataIC50: 1.00E+4nMpH: 7.5Assay Description:Binding Assays are based on the binding and displacement of an Alexa Fluor 647-labeled, ATP-competitive kinase inhibitors to the kinase of interest. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2019
Entry Details
US Patent