BDBM396115 6-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-6-ylmethyl)-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridin-7-ylamine::US10308667, Example 18

SMILES Cc1nc2nonc2c(N)c1Cc1ccc2OCCOc2n1

InChI Key InChIKey=JPIVYCAMMPUJEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 396115   

TargetGhrelin O-acyltransferase(Human)
Boehringer Ingelheim International

US Patent
LigandChemical structure of BindingDB Monomer ID 396115BDBM396115(6-(2,3-Dihydro-[1,4]dioxino[2,3-b]pyridin-6-ylmeth...)
Affinity DataIC50: 0.320nMAssay Description:Cells are plated with a density of 5000 cells/well in 384-well poly-D-lysin plates and incubated for 1 day at 37° C., 5% CO2 in DMEM medium, 10% FCS,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent