BDBM408111 (R)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-4-methylthiazole or (S)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)piperazin-1-yl)-4-methylthiazole::US10336775, Example 15

SMILES CC(N1CCN(CC1)c1nc(C)cs1)c1ccc2OCOc2c1

InChI Key InChIKey=RNRLOPAHHKHRGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 408111   

TargetProtein O-GlcNAcase(Human)
Asceneuron

US Patent
LigandChemical structure of BindingDB Monomer ID 408111BDBM408111((R)-2-(4-(1-(benzo[d][1,3]dioxol-5-yl)ethyl)pipera...)
Affinity DataIC50: 125nMAssay Description:5 μl of the appropriate concentration of a solution of inhibitor in McIlvaine's Buffer (pH 6.5) in 2% DMSO (for a dose response curve calcul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2020
Entry Details
US Patent