BDBM444942 6-(1-(2-chloro-4′-fluoro-5-methoxy-3′-(2,2,2-trifluoroethoxy)-[1,1′-biphenyl]-4-yl)-3-methylureido)-N-(pyrimidin-2-yl)pyridine-3-sulfonamide::US10668067, Example 3-1

SMILES CNC(=O)N(c1ccc(cn1)S(=O)(=O)Nc1ncccn1)c1cc(Cl)c(cc1OC)-c1ccc(F)c(OCC(F)(F)F)c1

InChI Key InChIKey=KSTKNRGXFQBWSQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 444942   

LigandChemical structure of BindingDB Monomer ID 444942BDBM444942(6-(1-(2-chloro-4′-fluoro-5-methoxy-3′-...)
Affinity DataIC50: 33nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent