BDBM50393511 CHEMBL2158056

SMILES CC(C)=CCn1nc(-c2cccc([N+](=O)[O-])c2)c2ncccc2c1=O

InChI Key InChIKey=VWEZZFADTFFJAD-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393511   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
University of Glasgow

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393511BDBM50393511(CHEMBL2158056)
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length PDE4A4 using cAMP as substrate by two-step radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
University of Glasgow

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393511BDBM50393511(CHEMBL2158056)
Affinity DataEC50:  15nMAssay Description:Induction of SQSTM1-dependent intracellular redistribution of GFP-tagged PDE4A4 assessed as maximal accretion of enzyme into fociMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed