BDBM50437951 CHEMBL2408922::US9403843, 24a
SMILES CC(C)C[C@H](NC(=O)[C@H]1O[C@@H]1C(O)=O)C(=O)Nc1nc(cs1)-c1ccc(F)cc1
InChI Key InChIKey=WVMZJHSGEWZNEO-QEJZJMRPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50437951
Affinity DataKi: 1.62E+3nMAssay Description:Inhibition of papain after using SucLLVYAMC as substrate by FRET assayMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Pig)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataKi: 6.00E+3nM ΔG°: -7.24kcal/molepH: 7.6 T: 30°CAssay Description:Full length porcine calpain (156 nM), or papain (236 pM) was added to a solution of 100 mM NaCl, 50 mM HEPES, pH 7.6, 1 mM TCEP, 30 μM Suc-LLVY-AM...More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Pig)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataKi: 6.02E+3nMAssay Description:Inhibition of pig full length Cal1 after using SucLLVYAMC as substrate by FRET assayMore data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 250nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 50nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair
TargetCalpain-1 catalytic subunit(Human)
The Trustees of Columbia University In The City of New York
US Patent
The Trustees of Columbia University In The City of New York
US Patent
Affinity DataIC50: 30nMpH: 7.4Assay Description:The Calbiochem InnoZyme activity kit was used for measuring the inhibition effect inhibitors on human erythrocyte calpain 1 activity. A calpain FRET ...More data for this Ligand-Target Pair