BDBM105309 US8575203, I-76

SMILES CCN1CCC(CC1)Nc1cnc2ccc(cc2c1)C#CCNC(=O)c1cccn([C@H](CO)c2cccc(F)c2)c1=O

InChI Key InChIKey=HXCWSWPMAGMRSS-WJOKGBTCSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105309   

Target3-phosphoinositide-dependent protein kinase 1(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM105309(US8575203, I-76)
Affinity DataIC50:  2nMAssay Description:The activity of the compounds according to the invention on the kinase PDK1 which inhibits the signal transduction pathway is determined in an in vit...More data for this Ligand-Target Pair
In DepthDetails US Patent