BDBM110129 US8609678, (R)-2-(3-(dimethylamino)pyrrolidin-1-yl)-N-(7-(hydroxyamino)-7-oxoheptyl)pyrimidine-5-carboxamide [182]

SMILES CN(C)[C@@H]1CCN(C1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO

InChI Key InChIKey=XUWURQSLAYAHGE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110129   

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 110129BDBM110129(US8609678, (R)-2-(3-(dimethylamino)pyrrolidin-1-yl...)
Affinity DataIC50: 33nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent

TargetHistone deacetylase 6(Human)
Acetylon Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 110129BDBM110129(US8609678, (R)-2-(3-(dimethylamino)pyrrolidin-1-yl...)
Affinity DataIC50: 80nMpH: 7.4Assay Description:Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2014
Entry Details
US Patent