BDBM112527 US8618103, I-23

SMILES CC(C)CC(=O)N1CC[C@@H](Nc2ncccc2-c2cnc3[nH]ccc3n2)C1

InChI Key InChIKey=XEGGRPXMVKBQIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 112527   

TargetTyrosine-protein kinase JAK2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 112527BDBM112527(US8618103, I-23)
Affinity DataIC50: 0.153nMpH: 7.2Assay Description:The kinase activity of all three JAK kinases is measured using a radioactive, end-point assay and with trace amounts of 33P-ATP. More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 112527BDBM112527(US8618103, I-23)
Affinity DataIC50: 10nMpH: 7.2Assay Description:The kinase activity of all three JAK kinases is measured using a radioactive, end-point assay and with trace amounts of 33P-ATP. More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
US Patent