BDBM11328 CHEMBL83508::Hydroxamate 9::N-hydroxy-2-[(4-methoxybenzene)sulfonamido]acetamide
SMILES COc1ccc(cc1)S(=O)(=O)NCC(=O)NO
InChI Key InChIKey=WLZISXXOYYGJNT-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 11328
Affinity DataKi: 20nMAssay Description:Inhibition of MMP12 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 29nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 30nM ΔG°: -10.3kcal/molepH: 7.4 T: 2°CAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 32nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Binding affinity towards (MMP-1) matrix metalloproteinase-1More data for this Ligand-Target Pair
Affinity DataKi: 110nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
Affinity DataKi: 120nMAssay Description:The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...More data for this Ligand-Target Pair
Affinity DataKi: 143nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
Affinity DataKi: 155nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
Affinity DataKi: >200nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
Affinity DataKi: 4.00E+3nMAssay Description:Inhibition of MMP7 (unknown origin)-mediated Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2 by fluorimetric assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+3nMAssay Description:Stromelysin inhibitory activity is based on the hydrolysis of substance P by recombinant human stromelysin to generate a fragment, substance P 7-11, ...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Universit£
Curated by ChEMBL
Universit£
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
TargetMeprin A subunit beta(Homo sapiens)
Fraunhofer Institute For Cell Therapy And Immunology Izi
Curated by ChEMBL
Fraunhofer Institute For Cell Therapy And Immunology Izi
Curated by ChEMBL
Affinity DataIC50: 9.02E+3nMAssay Description:Inhibition of recombinant human meprin beta expressed in yeast using Abz-YVAEAPK(Dnp)G-OH as substrate by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair