BDBM113564 US8633204, 302

SMILES Cc1nc(N)nc2n([C@H]3CC[C@@H](CC3)OCCO)c(=O)c(cc12)-c1cnn(C)c1

InChI Key InChIKey=BPRLASJBTWVPSB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113564   

LigandChemical structure of BindingDB Monomer ID 113564BDBM113564(US8633204, 302)
Affinity DataIC50: 22.3nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent