BDBM113570 US8633204, 317

SMILES COc1ccc(cn1)-c1cc2c(C)nc(N)nc2n([C@H]2C[C@@H](C2)OCC(N)=O)c1=O

InChI Key InChIKey=UTGVSQLUEPNLMK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 113570   

LigandChemical structure of BindingDB Monomer ID 113570BDBM113570(US8633204, 317)
Affinity DataIC50: 4.72nMpH: 7.4 T: 2°CAssay Description:Compounds of the present invention were evaluated for potency against PI3-Kα using an in vitro kinase assay. PI3-Kα activity is measured in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2014
Entry Details
US Patent