BDBM11605 β-CA inhibitor, 4::4-Amino-5-chloro-3-fluorobenzenesulfonamide::4-amino-3-chloro-5-fluorobenzene-1-sulfonamide::halogenosulfanilamide deriv. 6

SMILES Nc1c(F)cc(cc1Cl)S(N)(=O)=O

InChI Key InChIKey=XFMRTCFRRBAJHW-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11605   

TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  12nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  32nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  95nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  1.17E+3nM ΔG°:  -8.09kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  3.02E+3nM ΔG°:  -7.53kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  3.80E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Universit?? Degli Studi Di Firenze

LigandPNGBDBM11605(β-CA inhibitor, 4 | 4-Amino-5-chloro-3-fluoro...)
Affinity DataKi:  4.56E+3nM ΔG°:  -7.28kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed