BDBM13424 (15S)-14-hydroxy-4-methoxy-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-trien-5-yl sulfamate::oestrogen deriv. 9

SMILES COc1cc2C3CC[C@]4(C)C(O)CCC4C3CCc2cc1OS(N)(=O)=O

InChI Key InChIKey=RWIXFHUXVURZCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 13424   

TargetSteryl-sulfatase(Human)
St. Mary'S Hospital

LigandPNGBDBM13424((15S)-14-hydroxy-4-methoxy-15-methyltetracyclo[8.7...)
Affinity DataIC50: 34nMAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
St. Mary'S Hospital

LigandPNGBDBM13424((15S)-14-hydroxy-4-methoxy-15-methyltetracyclo[8.7...)
Affinity DataIC50: 376nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2007
Entry Details Article
PubMed