BDBM13455 N-[(3S)-3-(methylcarbamoyl)-2-[3-(4-methylphenyl)propanoyl]-1,2,3,4-tetrahydroisoquinolin-7-yl]sulfamic acid::Tetrahydroisoquinoline (TIQ) deriv. 10c

SMILES CNC(=O)[C@@H]1Cc2ccc(NS(O)(=O)=O)cc2CN1C(=O)CCc1ccc(C)cc1

InChI Key InChIKey=JCCIKOYRUWHOHY-IBGZPJMESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 13455   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

LigandPNGBDBM13455(N-[(3S)-3-(methylcarbamoyl)-2-[3-(4-methylphenyl)p...)
Affinity DataIC50:  1.98E+5nMAssay Description:The activity of PTP1B enzyme was assayed with DiFMUP as substrate. Hydrolysis of substrate was monitored on a Victor V plate reader (Wallac). Kinetic...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed