BDBM13966 2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pentylcarbamoyl)ethyl]phenyl}amidoformic acid)benzoic acid::2-{[4-((S)-2-tert-Butoxycarbonylamino-2-pentylcarbamoylethyl)phenyl]oxalylamino}benzoic Acid::Oxalylarylaminobenzoic Acid Analog 18

SMILES CCCCCNC(=O)[C@H](Cc1ccc(cc1)N(C(=O)C(O)=O)c1ccccc1C(O)=O)NC(=O)OC(C)(C)C

InChI Key InChIKey=IVZJQFCTICWGAA-NRFANRHFSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 13966   

TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13966(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pe...)
Affinity DataKi:  1.30E+4nMAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13966(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pe...)
Affinity DataKi:  1.58E+4nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13966(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pe...)
Affinity DataKi:  1.73E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM13966(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pe...)
Affinity DataKi:  1.73E+4nM ΔG°:  -6.43kcal/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM13966(2-({4-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-2-(pe...)
Affinity DataKi:  1.74E+4nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article