BDBM14639 3-(5-cyanopyrazin-2-yl)-1-(4-formyl-2-methoxyphenyl)urea::N-pyrazinylurea Analog 28

SMILES COc1cc(C=O)ccc1NC(=O)Nc1cnc(cn1)C#N

InChI Key InChIKey=CDGIKPAPLWNDJU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 14639   

TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

LigandPNGBDBM14639(3-(5-cyanopyrazin-2-yl)-1-(4-formyl-2-methoxypheny...)
Affinity DataIC50:  45nMAssay Description:Chk1 kinase activity was assayed in reaction buffer containing substrate, enzyme, and inhibitor in the presence of 5uM ATP/[gamma-33P] ATP. 33P incor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed